Colorectal
The following list provides a brief description of colorectal cancer trials that are open for recruitment in Western Australia. If you would like more information please follow the links provided, contact one of the trial sites or speak with your doctor.
Please note that this list is based on information provided to the Cancer Council by WA hospitals and may not include all clinical trials that are running in WA.
Where ‘N/A' appears - this means the lacking information has not been provided to date to the Cancer Council.
SCOT Study
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Registered Title |
Short Course Oncology Therapy - A Study of Adjuvant Chemotherapy in Colorectal Cancer. |
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Purpose |
This randomized phase III trial is studying chemotherapy given after surgery in treating patients with high-risk stage II or stage III colorectal cancer. |
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Lay Summary |
Drugs used in chemotherapy, such as oxaliplatin, fluorouracil, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known which combination chemotherapy regimen is more effective in treating patients who have undergone surgery for high-risk colorectal cancer. This study will investigate the efficacy of 3 months adjuvant chemotherapy versus 6 months in terms of 3-year disease free survival, overall survival, toxicity, cost effectiveness and quality of life. |
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WA Trial Sites |
RPH Medical Oncology |
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Links |
Acknowledgements: US National Library of Medicine, Australian New Zealand Clinical Trials Registry.
SIRFLOX Study
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Registered Title |
Randomised Comparative Study of folinic acid, 5-fluorouracil and oxaliplatin (FOLFOX6m) Plus SIR-Spheres(r) versus FOLFOX6m alone treatment on progression-free survival in first line patients with non-resectable Liver Metastases from Primary Colorectal Carcinoma. |
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Purpose |
This study is a randomized multi-centre trial that will assess the effect of adding SIRT, using SIR-Spheres microspheres, to a standard chemotherapy regimen of FOLFOX as first line therapy in patients with non-resectable liver metastases from primary colorectal adenocarcinoma. |
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Lay Summary |
N/A |
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WA Trial Sites |
SCGH Medical Oncology
RPH Medical Oncology
The Mount Hospital |
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Links |
Acknowledgements: US National Library of Medicine
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