Head and Neck
The following list provides a brief description of head and neck cancer trials that are open for recruitment in Western Australia. If you would like more information please follow the links provided, contact one of the trial sites or speak with your doctor.
Please note that this list is based on information provided to the Cancer Council by WA hospitals and may not include all clinical trials that are running in WA.
Where ‘N/A' appears - this means the lacking information has not been provided to date to the Cancer Council.
Decibel
| Registered Title | Phase 1 Randomized, Double-Blind, Placebo-Controlled, Single Ascending-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DB-020 in Healthy Volunteers |
| Purpose | This research project is being conducted to investigate the safety, tolerability, and pharmacokinetics of single ascending dose DB-020 when administered via intratympanic injection to healthy adult volunteers. |
| Lay Summary | N/A |
| WA Trial Sites |  (oncology) Ph. 08 615 26530 |
| Links | Australian and New Zealand Clinical Trials Registry |
Acknowledgements: Australian and New Zealand Clinical Trials Registry
LIBRETTO-531
| Registered Title | A Multicenter, Randomized, Open-label, Phase 3 Trial Comparing Selpercatinib to Physicians Choice of Cabozantinib or Vandetanib in Patients With Progressive, Advanced, Kinase Inhibitor Naïve, RET-Mutant Medullary Thyroid Cancer (LIBRETTO-531) |
| Purpose | The purpose for this study is to see if the study drug selpercatinib is safe and more effective compared to a standard treatment in participants with rearranged during transfection (RET)-mutant medullary thyroid cancer (MTC) that cannot be removed by surgery or has spread to other parts of the body. Participants who are assigned to the standard treatment and discontinue due to progressive disease have the option to potentially crossover to selpercatinib. |
| Lay Summary | N/a |
| WA Trial Sites |  SCGH Medical Oncology Ph. (08) 6383 3000 |
| Links | US National Library of Medicine |
Acknowledgements: US National Library of Medicine
