Quality of Life, Survivorship and Lifestyle

The following list provides a brief description of clinical trials that are investigating the quality of life, survivorship and lifestyle of cancer patients and that are currently recruiting participants in Western Australia. If you would like more information please follow the links provided, contact one of the trial sites or speak with your doctor.

Please note that this list is based on information provided to the Cancer Council by WA hospitals and may not include all clinical trials that are running in WA.

Where ‘N/A' appears - this means the lacking information has not been provided to date to the Cancer Council.

 

EXERCISE AND MELANOMA

Registered Title

The effects of structured exercise on melanoma patients receiving immunotherapy

Purpose  To determine the effects of an 8-week, supervised exercise program on melanoma
patients receiving checkpoint inhibitor therapy.
Lay Summary N/A 
WA Trial Sites Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au.
 Links   ECU Exercise Medicine Research Institute

 

RESISTANCE EXERCISE AND OVARIAN CANCER

Registered Title   The effect of a supervised resistance exercise intervention on muscle in advanced-stage ovarian cancer survivors who have completed first line treatment
Purpose  To investigate the effect of a 12-week supervised resistance exercise intervention on
muscle mass and density, muscle strength and physical function in ovarian cancer survivors who have completed first line treatment.
Lay Summary  N/A
WA Trial Sites Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au
Links  ECU Exercise Medicine Research Institute

 

EXERCISE AND TUMOUR HYPOXIA

Registered Title  Exercise as adjuvant therapy to increase prostate tumour oxygenation and improve the effectiveness of
radiotherapy
 Purpose To assess the feasibility of exercise training immediately before radiotherapy sessions
and to explore physiological changes that may be associated with a favourable treatment outcome
Lay Summary N/A
WA Trial Sites Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au
 Links  ECU Exercise Medicine Research Institute

 

ACTIVE SURVEILLANCE

Registered Title   A randomized controlled trial of exercise medicine for men undergoing active surveillance for prostate
cancer
Purpose  To determine the efficacy of implementing a program of exercise medicine specifically
prescribed to delay (or even prevent) transition to active therapies and impede PCa progression
Lay Summary  N/A
WA Trial Sites Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au
 Links  ECU Exercise Medicine Research Institute

 

ECCENTRIC EXERCISE AND PROTEIN SUPPLEMENTATION IN PROSTATE CANCER

Registered Title The Effects of Accentuated Eccentric Resistance Training on Muscle Mass and Strength in Prostate Cancer Patients Undergoing Androgen-Deprivation Therapy
Purpose To examine muscle mass and strength outcomes after 36 sessions of eccentric exercise
and whey protein supplementation.
Lay Summary  N/A
WA Trial Sites Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au
Links  ECU Exercise Medicine Research Institute

GUT HEALTH - PCFA

Registered Title An exploratory study to determine if exercise can impact the gut microbiota composition of men receiving androgen suppression therapy for prostate cancer 
Purpose The overall aim of this exploratory study is to determine the effect of exercise medicine
on the gut microbiota and its metabolome of men receiving ADT for prostate cancer
Lay Summary The side effects of prostate cancer treatments can result in an imbalance of bacteria in the gut causing constipation, diarrhoea, incontinence and nausea. This study will explore whether exercise can improve the gut bacteria of prostate cancer patients receiving androgen deprivation therapy. The project will involve prostate cancer patients in a 12 week exercise medicine program. If successful, the findings of this study could significantly improve the well-being of prostate cancer survivors.
WA Trial Sites Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au
Links  ECU Exercise Medicine Research Institute

 

AREA

Registered Title Randomised study to evaluate the impact of Aerobic and Resistance Exercise on fatigue in patients with advanced breast cancer (AREA study)
Purpose  The study will assess the feasibility of a specified exercise program in patients with advanced breast cancer and its impact on improving fatigue.
Lay Summary The intervention is a 6 Week Exercise Program which will be offered as 1 hour sessions twice a week for 6 weeks.
The Exercise sessions include:
1. 10 minutes of warm-up using the large muscle groups in arms & legs on a treadmill, bike or rowing machine (mild paced and customized to individual capability)
2. 30 minutes of resistance exercise against own body weight or the weight of an object using arms and legs (customized to individual capability)
3. The last 10 minutes is for stretching exercises.
WA Trial Sites  Ph. (08) 6500 5555
Links  Australian New Zealand Clinical Trials Registry

Acknoweledgments: Australian New Zealand Clinical Trials Registry


FROCS

Registered Title Mindfulness Based Cognitive Therapy for Fear of Recurrence in Ovarian Cancer Survivors. (FROCS)
Purpose  This study will determine the effect of mindfulness based cognitive therapy on the fear of recurrence in ovarian cancer survivors. Who is it for? You may be eligible to join this study if you are aged 18 years or above and have been diagnosed with ovarian cancer, have completed all hospital based adjuvant treatment and are now disease free. Study details All participants will receive the same intervention and will involve intensive training and practice in mindfulness based cognitive therapy. Treatment is designed as an 8 week course of 2-2.5 hour small group sessions once weekly with approximately 8-15 individuals in each group. Sessions are run at locations in Shenton Park, Duncraig and East Fremantle by the Cancer Council WA, or by SolarisCare Foundation, at Sir Charles Gardner Hospital in Nedlands. Courses take place during the day and are free of charge. The groups will be run by experienced clinicians in psychotherapy, counselling and meditation and will have a clinician manual and a participant workbook outlining the themes and exercises for each week. Group members will be expected to practice skills between sessions. Participants will be asked to answer questionnaires before, during and after the group sessions to collect information on how participants are feeling.
Lay Summary  N/A
WA Trial Sites  
St John of God Subiaco Ph. (08) 6465 9204
Links  Australian New Zealand Clinical Trials Registry

Acknoweledgments:  Australian New Zealand Clinical Trials Registry

 

Finding My Way

Registered Title

Finding My Way - Coping with Cancer Online

Purpose

Finding My Way is an internet based intervention that provides a convenient, user friendly way to gain information and/or skills to improve your physical and mental well being during your treatment for cancer.

Lay Summary

Please visit the Finding My Way website for more information.

WA Trial Sites

Flinders University

Email: info@findingmyway.org.au

Links

Finding My Way

 

GAP4 - MOVEMBER

Title

INTense Exercise foR surVivAL among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL – MCRPC) (GAP4).

Purpose

The primary objective of this study is to determine if high intensity aerobic and resistance training plus psychosocial support increases overall survival compared to psychosocial support alone in prostate cancer patients. The term psychosocial relates to the interrelation of psychological and social thoughts and behaviours, thus support of this nature will be provided to all participants.

Lay Summary

Exercise has been established as a safe and effective activity leading to improved physical function and quality of life in men with prostate cancer. However, little information exists regarding whether exercise can increase overall survival and reduce disease progression, skeletal-related events, and pain in patients with metastatic castrate-resistant prostate cancer.

WA Trial Sites

Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au

Links

ECU Exercise Medicine Research Institute

 

EXERCISE AND SUPPLEMENTATION INTERVENTION IN PROSTATE CANCER

Title

Effects of a combined exercise and supplement intervention on muscle mass in prostate cancer patients on androgen deprivation therapy

Purpose

To examine the efficacy of creatine supplementation in addition to weight training on
muscle mass, physical function and quality of life in men with prostate cancer receiving ADT

Lay Summary

N/A

WA Trial Sites

Edith Cowan University Exercise Medicine Research Institute.
Patients who may be eligible for any of these projects can contact our team for further information on 6304 3444 or at trials@exercisemedicine.org.au

Links

ECU Exercise Medicine Research Institute

 

Sexual healing

Registered Title

A Randomised, Controlled Trial on the Effect of Pre-Operative Sexual Counselling on Sexuality and Quality of Life after Risk-Reducing Salpingo-oophrectomy.

Purpose

This study will determine the effect of pre-operative sexual counselling on sexuality and quality of life after risk reducing salpingo-oophorectomy (RRSO) in women at high risk of ovarian cancer. 

Lay Summary

Who is it for?

You may be eligible to join this study if you are aged 18 years or above, at high risk of ovarian cancer and have decided to undergo risk-reducing salpingo-oophorectomy.

Study details:

Participants in this study are randomly allocated (by chance) to one of two groups. Participants in one group will receive a single pre-operative counselling session with a sexologist to discuss the potential effects of surgery on sexual function and physical changes, potential changes to intimacy, loss of sexual self-esteem related to body image changes, menopausal symptoms and confidence, changes to sexual response such as reduced arousal, loss of libido, difficulty reaching orgasm, menopausal symptoms related to treatment including hot flushes/night sweats, disturbed sleep, poor memory and weight gain, all of which may impact on one’s sexual self esteem, sexual functioning and general wellbeing (quality of life).

While participants in the other group will receive routine care which is the initial consultation with your gynaecologic oncology specialist who may or may not discuss such issues with you. Participants will be followed-up for up to 12 months post-surgery to determine the effect on sexual function, the prevalence and severity of sexual difficulties after RRSO, and any other factors that significantly affect sexual function and quality of life. Serum testosterone levels will also be tested to determine whether there is a correlation with sexual function after RRSO.

WA Trial Sites

St John of God Healthcare logo

St John of God
Ph. (08) 6465 9204

Links

Australian New Zealand Clinical Trials Registry

Acknowledgements: Australian and New Zealand Clinical Trials Registry

 

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