Quality of Life, Survivorship and Lifestyle

The following list provides a brief description of clinical trials that are investigating the quality of life, survivorship and lifestyle of cancer patients and that are currently recruiting participants in Western Australia. If you would like more information please follow the links provided, contact one of the trial sites or speak with your doctor.

Please note that this list is based on information provided to the Cancer Council by WA hospitals and may not include all clinical trials that are running in WA.

Where ‘N/A' appears - this means the lacking information has not been provided to date to the Cancer Council.

 

AREA

Registered Title Randomised study to evaluate the impact of Aerobic and Resistance Exercise on fatigue in patients with advanced breast cancer (AREA study)
Purpose  The study will assess the feasibility of a specified exercise program in patients with advanced breast cancer and its impact on improving fatigue.
Lay Summary The intervention is a 6 Week Exercise Program which will be offered as 1 hour sessions twice a week for 6 weeks.
The Exercise sessions include:
1. 10 minutes of warm-up using the large muscle groups in arms & legs on a treadmill, bike or rowing machine (mild paced and customized to individual capability)
2. 30 minutes of resistance exercise against own body weight or the weight of an object using arms and legs (customized to individual capability)
3. The last 10 minutes is for stretching exercises.
WA Trial Sites  Ph. (08) 6500 5555
Links  Australian New Zealand Clinical Trials Registry

Acknoweledgments: Australian New Zealand Clinical Trials Registry

 

FROCS

Registered Title Mindfulness Based Cognitive Therapy for Fear of Recurrence in Ovarian Cancer Survivors. (FROCS)
Purpose  This study will determine the effect of mindfulness based cognitive therapy on the fear of recurrence in ovarian cancer survivors. Who is it for? You may be eligible to join this study if you are aged 18 years or above and have been diagnosed with ovarian cancer, have completed all hospital based adjuvant treatment and are now disease free. Study details All participants will receive the same intervention and will involve intensive training and practice in mindfulness based cognitive therapy. Treatment is designed as an 8 week course of 2-2.5 hour small group sessions once weekly with approximately 8-15 individuals in each group. Sessions are run at locations in Shenton Park, Duncraig and East Fremantle by the Cancer Council WA, or by SolarisCare Foundation, at Sir Charles Gardner Hospital in Nedlands. Courses take place during the day and are free of charge. The groups will be run by experienced clinicians in psychotherapy, counselling and meditation and will have a clinician manual and a participant workbook outlining the themes and exercises for each week. Group members will be expected to practice skills between sessions. Participants will be asked to answer questionnaires before, during and after the group sessions to collect information on how participants are feeling.
Lay Summary  N/A
WA Trial Sites  
St John of God Subiaco Ph. (08) 6465 9204
Links  Australian New Zealand Clinical Trials Registry

Acknoweledgments:  Australian New Zealand Clinical Trials Registry

 

Finding My Way

Registered Title

Finding My Way - Coping with Cancer Online

Purpose

Finding My Way is an internet based intervention that provides a convenient, user friendly way to gain information and/or skills to improve your physical and mental well being during your treatment for cancer.

Lay Summary

Please visit the Finding My Way website for more information.

WA Trial Sites

Flinders University

Email: info@findingmyway.org.au

Links

Finding My Way

 

Improving sexual health in men with prostate cancer

Title

Improving sexual health in men with prostate cancer: randomised controlled trial of exercise and psychosexual therapies.

Purpose

This project examines whether exercise aids in the management of sexual dysfunction and explores if an integrated treatment model incorporating pharmacological, exercise and psychosexual therapies maximises improvement in sexual health.

Lay Summary

Sexual dysfunction is one of the most common and distressing side effects of prostate cancer. Despite being a critical survivorship care issue, there is a clear gap in knowledge surrounding the optimal treatment of sexual dysfunction in men with prostate cancer.

  • Inclusion criteria: Concerned by your sexual wellbeing; prior/current treatment for prostate cancer including prostatectomy, radiotherapy or ADT.
  • Exclusion criteria: Non-nerve sparing prostatectomy; > 6 months since prostatectomy or completion of radiotherapy or ADT; incontinence defined as requiring the use of > 1 pad in a 24-hour period.

WA Trial Sites

Edith Cowan University Exercise Medicine Research Institute.

Sites available: Joondalup, Mt Lawley, Crawley, Fremantle and Murdoch.

Patients who may be eligible for any of these projects can contact our team for further information on 6304 2329 or at emri@ecu.edu.au.

Links

ECU Exercise Medicine Research Institute

 

INTense Exercise foR surVivAL among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL – MCRPC) (GAP4)

Title

INTense Exercise foR surVivAL among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL – MCRPC) (GAP4).

Purpose

The primary objective of this study is to determine if high intensity aerobic and resistance training plus psychosocial support increases overall survival compared to psychosocial support alone in prostate cancer patients. The term psychosocial relates to the interrelation of psychological and social thoughts and behaviours, thus support of this nature will be provided to all participants.

Lay Summary

Exercise has been established as a safe and effective activity leading to improved physical function and quality of life in men with prostate cancer. However, little information exists regarding whether exercise can increase overall survival and reduce disease progression, skeletal-related events, and pain in patients with metastatic castrate-resistant prostate cancer.

WA Trial Sites

Edith Cowan University Exercise Medicine Research Institute.

Patients who may be eligible for any of these projects can contact our team for further information on 6304 2329 or at emri@ecu.edu.au.

Links

ECU Exercise Medicine Research Institute

 

 

Program of Exercise Medicine for Men on Prostate Cancer Active Surveillance

Title

Preliminary Efficacy of Implementing a Program of Exercise Medicine for Men on Prostate Cancer Active Surveillance - A Pilot Study.

Purpose

Our aim is to determine the feasibility and efficacy of implementing a program of exercise medicine specifically prescribed to ameliorate the primary physical and mental health problems faced by men on prostate cancer active surveillance and explore potential mechanisms underlying the influence of physical exercise on markers of disease progression.

Lay Summary

Exercise has been established to be safe and result in improved physical function and quality of life for cancer patients. Our team and others have consistently demonstrated that exercise improves physical and mental health in men with prostate cancer during and following completion of therapeutic interventions. More specifically, resistance and aerobic exercise have been shown to enhance the musculoskeletal system, improve cardiorespiratory capacity, prevent functional decline, improve sexual health, body composition, endocrine and immune function as well as overall quality of life. A recent and very exciting discovery suggests that, in some cases, exercise may actually suppress tumour progression. However, all of the exercise clinical trials to date have included patients during or following surgery, radiation or hormone treatment. There are no established recommendations for improving active surveillance adherence, slowing disease progression, delaying time to active curative treatment, or reducing active surveillance-specific anxiety and distress.

WA Trial Sites

Edith Cowan University Exercise Medicine Research Institute.

Patients who may be eligible for any of these projects can contact our team for further information on 6304 2329 or at emri@ecu.edu.au.

Links

ECU Exercise Medicine Research Institute

 

Sexual healing

Registered Title

A Randomised, Controlled Trial on the Effect of Pre-Operative Sexual Counselling on Sexuality and Quality of Life after Risk-Reducing Salpingo-oophrectomy.

Purpose

This study will determine the effect of pre-operative sexual counselling on sexuality and quality of life after risk reducing salpingo-oophorectomy (RRSO) in women at high risk of ovarian cancer. 

Lay Summary

Who is it for?

You may be eligible to join this study if you are aged 18 years or above, at high risk of ovarian cancer and have decided to undergo risk-reducing salpingo-oophorectomy.

Study details:

Participants in this study are randomly allocated (by chance) to one of two groups. Participants in one group will receive a single pre-operative counselling session with a sexologist to discuss the potential effects of surgery on sexual function and physical changes, potential changes to intimacy, loss of sexual self-esteem related to body image changes, menopausal symptoms and confidence, changes to sexual response such as reduced arousal, loss of libido, difficulty reaching orgasm, menopausal symptoms related to treatment including hot flushes/night sweats, disturbed sleep, poor memory and weight gain, all of which may impact on one’s sexual self esteem, sexual functioning and general wellbeing (quality of life).

While participants in the other group will receive routine care which is the initial consultation with your gynaecologic oncology specialist who may or may not discuss such issues with you. Participants will be followed-up for up to 12 months post-surgery to determine the effect on sexual function, the prevalence and severity of sexual difficulties after RRSO, and any other factors that significantly affect sexual function and quality of life. Serum testosterone levels will also be tested to determine whether there is a correlation with sexual function after RRSO.

WA Trial Sites

St John of God Healthcare logo

St John of God
Ph. (08) 6465 9204

Links

Australian New Zealand Clinical Trials Registry

Acknowledgements: Australian and New Zealand Clinical Trials Registry

 

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