Skin (non-melanoma)


The following list provides a brief description of skin cancer trials that are open for recruitment in Western Australia. If you would like more information please follow the links provided, contact one of the trial sites or speak with your doctor.

Please note that this list is based on information provided to the Cancer Council by WA hospitals and may not include all clinical trials that are running in WA.

Where ‘N/A' appears - this means the lacking information has not been provided to date to the Cancer Council.

 

C-POST / R2810-ONC-1788

Registered Title Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma
Purpose The primary objective of the study is to compare disease-free survival (DFS) of patients with high-risk cutaneous squamous cell carcinoma (CSCC) treated with adjuvant cemiplimab, versus those treated with placebo, after surgery and radiation therapy (RT).
Lay Summary  N/A
WA Trial Sites  Medical Oncology Ph. (08) 6383 3000
Links  US National Library of Medicine

Acknowledgements: US National Library of Medicine

 

TACTI-002

Registered Title  TACTI-002 (Two ACTive Immunotherapeutics): A Multicenter, Open Label, Phase II Study in Patients With Previously Untreated Unresectable or Metastatic Non-small Cell Lung Cancer (NSCLC), or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic Squamous Head and Neck Cancer (HNSCC) Receiving the Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) in Combination With Pembrolizumab (PD-1 Antagonist)
Purpose  Evaluate the safety and efficacy of the combination of eftilagimod alpha with pembrolizumab in non-small cell lung carcinoma and head and neck carcinoma patients.
Lay Summary  N/A
WA Trial Sites   Ph. (08) 6465 9204
Links  US National Library of Medicine

Acknowledgements: US National Library of Medicine

 

R2810-ONC-1540

Registered Title A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients With Advanced Cutaneous Squamous Cell Carcinoma
Purpose  To estimate the clinical benefit of cemiplimab monotherapy for patients with metastatic
(nodal or distant) cutaneous squamous cell carcinoma (CSCC) (Groups 1 and 3) or with
unresectable locally advanced CSCC (Group 2), or with advanced CSCC [metastatic (nodal or
distal) or unresectable locally advanced] treated (Group 4) as measured by overall response
rate (ORR), according to central review.
Lay Summary  N/A
WA Trial Sites  Medical Oncology Ph. (08) 6383 3000
 Links  US National Library of Medicine

Acknowledgements: US National Library of Medicine